Beilstein J. Nanotechnol.2016,7, 1208–1218, doi:10.3762/bjnano.7.112
; quaternarysystem; sodium alginate; Introduction
Tuberculosis, together with HIV infection, is a leading cause of death with 1.5 million deaths in 2014 worldwide [1]. The biggest challenges regarding a successful treatment of tuberculosis infections are the necessary high dosages and various side effects of
than the DGI of the 1:100 control.
Preparation of the microparticulate systems
The quaternarysystem: ISN–β-cyclodextrin–alginate–chitosan (system 1) was obtained using kneading, the mass ratio of components was 1:2.36:4:4. At the first stage, the binary system ISN–β-cyclodextrin was obtained by
PDF
Figure 1:
Molecular structures of INH (1) and ISN (2).